MRTF-A-IN-1

MRTF-A-in-1 (Compound 14) is MRTF-A inhibitor. MRTF-A-in-1 can inhibit cell proliferation and induce HCC cell aging[1].

Product Specifications

UNSPSC

12352211

Target

Ras

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/mrtf-a-in-1.html

Smiles

CC(C1=CC=C(C2=CC=CC(NC3=NC4=C(C=CC=C4)N3)=C2)C=C1)C

Molecular Formula

C22H21N3

Molecular Weight

327.42

References & Citations

[1]Franz MJ, et al. Identification of novel inhibitors of the transcriptional coactivator MRTF-A for HCC therapy. Mol Ther Oncol. 2024 Aug 6;32 (3) :200855.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS7030637-01 0.02 mg

Recombinant Bovine SUN domain-containing protein 3 (SUN3)

Ask

View Details

MBS7030637-02 0.1 mg

Recombinant Bovine SUN domain-containing protein 3 (SUN3)

Ask

View Details

MBS7030637-03 5x 0.1 mg

Recombinant Bovine SUN domain-containing protein 3 (SUN3)

Ask

View Details

251837-HRP 100 µL

SMAD7 (SMAD Family Member 7, CRCS3, FLJ16482, MADH7, MADH8) (HRP)

Ask

View Details

MBS1278906-01 0.01 mg Plasmid + 0.2 mL Glycerol-Stock

AUP1 cDNA Clone

Ask

View Details

MBS1278906-02 5x 0.01 mg Plasmid + 5x 0.2 mL Glycerol-Stock

AUP1 cDNA Clone

Ask

View Details