MRTF-A-IN-1
MRTF-A-in-1 (Compound 14) is MRTF-A inhibitor. MRTF-A-in-1 can inhibit cell proliferation and induce HCC cell aging[1].
Product Specifications
UNSPSC
12352211
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/mrtf-a-in-1.html
Smiles
CC(C1=CC=C(C2=CC=CC(NC3=NC4=C(C=CC=C4)N3)=C2)C=C1)C
Molecular Formula
C22H21N3
Molecular Weight
327.42
References & Citations
[1]Franz MJ, et al. Identification of novel inhibitors of the transcriptional coactivator MRTF-A for HCC therapy. Mol Ther Oncol. 2024 Aug 6;32 (3) :200855.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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