MIPS-21335
MIPS-21335 is a PI3KC2α inhibitor with an IC50 of 7 nM. MIPS-21335 also inhibits PI3KC2β, p110α, p110β and p110δ, with IC50 values of 43, 140, 386 and 742 nM, respectively. MIPS-21335 has antithrombotic effect. MIPS-21335 can be used for the researches of cardiovascular disease and metabolic disease, such as thrombosis and hyperlipidemia[1][2].
Product Specifications
CAS Number
2569296-51-9
UNSPSC
12352005
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/mips-21335.html
Purity
99.61
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
COC1=C2N=C(N3CCN=C3C2=CC=C1OCC4=CC([N+]([O-])=O)=CC=C4)NC(C5=CN=C(C=C5)N)=O
Molecular Formula
C24H21N7O5
Molecular Weight
487.47
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI3KC2α; PI3KC2β
Available Sizes
Frequently Asked Questions
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