(R)-Simurosertib
Product Specifications
UNSPSC Description
(R)-Simurosertib ((R)-TAK-931) is the (R)-enantiomer of Simurosertib. Simurosertib (TAK-931) is an orally active, selective and ATP-competitive cell division cycle 7 (CDC7) kinase inhibitor, with an IC50 of [1].
Target Antigen
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/r-simurosertib.html
Purity
99.58
Solubility
DMSO : 75 mg/mL (ultrasonic)
Smiles
O=C(C1=C(N2)C=C(C3=CNN=C3C)S1)N=C2[C@H]4CC5CCN4CC5
Molecular Weight
341.43
References & Citations
[1]K Iwai, et al. A novel CDC7-selective inhibitor TAK-931 with potent antitumor activity. European Journal of Cancer , 2016 , 69 (1) :S34.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-100888A/R-Simurosertib-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-100888A/R-Simurosertib-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1330782-69-8
Available Sizes
Curated Selection
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