PDE6G Rabbit pAb
This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009],
Product Specifications
Background
Product Name Alternative
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma (GMP-PDE gamma; EC 3.1.4.35)
UniProt
P18545
Swiss Prot
P18545
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human PDE6G AA range: 10-90
Target
PDE6G
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; ELISA
Concentration
1 mg/ml
Dilution
IHC-p 1:50-200, ELISA (peptide) 1:5000-20000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Plasma membrane, photoreceptor disc membrane
Other Product Names
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma (GMP-PDE gamma; EC 3.1.4.35)
Gene ID (Human)
5148
Available Sizes
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