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Anti-Hu CD303 Alexa Fluor® 647

CD303 is an approximately 38 kDa type II transmembrane glycoprotein with an extracellular C-type lectin domain. It is a specific marker of plasmacytoid dendritic cells, and plays roles in capturing of pathogen-related oligosaccharide-containing antigens by them, and in their presentation to T cells. CD303 also mediates a potent inhibition of interferon alpha/beta production in plasmacytoid dendritic cells, thus it represents a potential target for lupus erythematosus therapy.

Product Specifications

Certification

RUO

Reactivity

Human

Immunogen

CD303 ectodomain fused with human IgG Fc domain

Target Antigen

CD303

Clone

15E3

Applications

ICC, FC, IHC-F

Format

Alexa Fluor® 647

Buffer

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Storage Conditions

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Specificity

The mouse monoclonal antibody 15E3 recognizes an extracellular epitope of human CD303, a transmembrane glycoprotein expressed on plasmacytoid dendritic cells.

Applications Notes

6

Isotype

Mouse IgG1 kappa

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