ZZW-115 (hydrochloride)
ZZW-115 hydrochloride is a potent NUPR1 inhibitor, with a Kd of 2.1 μM. ZZW-115 hydrochloride induces tumor cell death by necroptosis and apoptosis. Anticancer activity[1][2].
Product Specifications
CAS Number
10122-45-9
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/zzw-115-hydrochloride.html
Purity
98.09
Solubility
DMSO : 83.33 mg/mL (ultrasonic) |H2O : 60 mg/mL (ultrasonic)
Smiles
FC(C(C=C1N2CCCN3CCN(CCN(C)C)CC3)=CC=C1SC4=C2C=CC=C4)(F)F.[H]Cl.[H]Cl.[H]Cl
Molecular Formula
C24H34Cl3F3N4S
Molecular Weight
573.97
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Citation 01
BMC Med. 2022 Oct 19;20 (1) :365.|J Cell Mol Med. 2025 Apr;29 (7) :e70519.|Mol Cancer. 2024 May 28;23 (1) :113.|Research Square Preprint. 2024 Feb 20.
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