Phospho-Stat6 (Tyr641) Rabbit mAb Antibody Conjugate

<strong>Phospho-Stat6 (Tyr641) Rabbit mAb Antibody Conjugate </strong>_x000D_ <strong>Catalog number:</strong> B2018396_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 Tests_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8 °C_x000D_ <strong>Keywords:</strong> Signal transducer and activator of transcription 6, IL-4 Stat_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Rahal OM, Wolfe AR, Mandal PK, Larson R, Tin S, Jimenez C, Zhang D, Horton J, Reuben JM, McMurray JS, Woodward WA. Blocking Interleukin (IL)4- and IL13-Mediated Phosphorylation of STAT6 (Tyr641) Decreases M2 Polarization of Macrophages and Protects Against Macrophage-Mediated Radioresistance of Inflammatory Breast Cancer Int J Radiat Oncol Biol Phys. 2018 Mar 15;100(4):1034-1043._x000D_ 2: Corrick KL, Stec MJ, Merritt EK, Windham ST, Thomas SJ, Cross JM, Bamman MM. Serum from human burn victims impairs myogenesis and protein synthesis in primary myoblasts Front Physiol. 2015 Jun 16;6:184._x000D_ 3: Chen H, Sun H, You F, Sun W, Zhou X, Chen L, Yang J, Wang Y, Tang H, Guan Y, Xia W, Gu J, Ishikawa H, Gutman D, Barber G, Qin Z, Jiang Z. Activation of STAT6 by STING is critical for antiviral innate immunity Cell. 2011 Oct 14;147(2):436-46._x000D_ 4: Lahiri S, Seidel R, Engelhard M, Becker CF. Photocontrol of STAT6 dimerization and translocation Mol Biosyst. 2010 Dec;6(12):2423-9._x000D_ 5: Mandal PK, Morlacchi P, Knight JM, Link TM, Lee GR 4th, Nurieva R, Singh D, Dhanik A, Kavraki L, Corry DB, Ladbury JE, McMurray JS. Targeting the Src Homology 2 (SH2) Domain of Signal Transducer and Activator of Transcription 6 (STAT6) with Cell-Permeable, Phosphatase-Stable Phosphopeptide Mimics Potently Inhibits Tyr641 Phosphorylation and Transcriptional Activity J Med Chem. 2015 Nov 25;58(22):8970-84._x000D_ 6: Sung SC, Cheng CH, Chou CM, Chu CY, Chen GD, Hwang PP, Huang FL, Huang CJ. Expression and characterization of a constitutively active STAT6 from Tetraodon Fish Shellfish Immunol. 2010 May-Jun;28(5-6):819-28._x000D_ 7: Benghalem I, Meziane W, Hadjidj Z, Ysmail-Dahlouk L, Belamri A, Mouhadjer K, Aribi M. High-density lipoprotein immunomodulates the functional activities of macrophage and cytokines produced during ex vivo macrophage-CD4(+) T cell crosstalk at the recent-onset human type 1 diabetes Cytokine. 2017 Aug;96:59-70._x000D_ 8: Bredholt T, Ersvær E, Erikstein BS, Sulen A, Reikvam H, Aarstad HJ, Johannessen AC, Vintermyr OK, Bruserud Ø, Gjertsen BT. Distinct single cell signal transduction signatures in leukocyte subsets stimulated with khat extract, amphetamine-like cathinone, cathine or norephedrine BMC Pharmacol Toxicol. 2013 Jul 11;14:35._x000D_ 9: Maiti NR, Sharma P, Harbor PC, Haque SJ. Serine phosphorylation of Stat6 negatively controls its DNA-binding function J Interferon Cytokine Res. 2005 Sep;25(9):553-63._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/27717877">10: Ysmail-Dahlouk L, Nouari W, Aribi M. 1,25-dihydroxyvitamin D(3) down-modulates the production of proinflammatory cytokines and nitric oxide and enhances the phosphorylation of monocyte-expressed STAT6 at the recent-onset type 1 diabetes Immunol Lett. 2016 Nov;179:122-130. </a>_x000D_ _x000D_ <strong>Products Related to Phospho-Stat6 (Tyr641) Rabbit mAb Antibody Conjugate can be found at</strong> <a href="https://moleculardepot.com/product-category/Antibodies/"> Antibodies</a>