Slingshot inhibitor D3

Slingshot inhibitor D3 is a potent, selective, reversible and competitive inhibitor of Slingshot. The IC50 value for Slingshot 1 is 3 μM and the Ki value for Slingshot 2 is 3.9 μM. Slingshot inhibitor D3 has similar inhibitory activities toward both Slingshot 1 and Slingshot 2[1].

Product Specifications

CAS Number

[1715076-35-9]

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/slingshot-inhibitor-d3.html

Concentration

10mM

Purity

99.46

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=CC=C(C=C1)COC2=CC=C(C=C2)/C=C(C3=O)\SC(N3C4=CC=CC=C4C)=S)O

Molecular Formula

C25H19NO4S2

Molecular Weight

461.55

References & Citations

[1]Li KS, et al. Identification of para-Substituted Benzoic Acid Derivatives as Potent Inhibitors of the Protein Phosphatase Slingshot. ChemMedChem. 2015;10 (12) :1980-1987.