Enocitabine
Product Specifications
UNSPSC Description
Enocitabine is a nucleoside analog, and is a potent DNA replication inhibitor, and a DNA chain terminator. Enocitabine inhibits the replication of human cytomegalovirus. Enocitabine has antileukemic and antiviral activities[1][2][3].
Target Antigen
CMV; DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Anti-infection;Cell Cycle/DNA Damage
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/enocitabine.html
Purity
99.32
Solubility
H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
CCCCCCCCCCCCCCCCCCCCCC(NC(C=CN1[C@H]2[C@@H](O)[C@H](O)[C@H](O2)CO)=NC1=O)=O
Molecular Weight
565.78
References & Citations
[1]Hamada A, et al. Clinical pharmacokinetics of cytarabine formulations.Clin Pharmacokinet. 2002;41(10):705-18.|[2]Nagasawa M, et al.In vitro combined effects of pirarubicin (THP) and various antitumor drugs on human tumor cell lines. Gan To Kagaku Ryoho. 1990 Apr;17(4 Pt 1):633-8.|[3]Nakamura K, et al. Antiviral effect of antileukemic drugs N4-behenoyl-1-beta-D-arabinofuranosylcytosine (BH-AC) and 2,2'-anhydro-1-beta-D-arabinofuranosylcytosine (cyclo-C) against human cytomegalovirus. J Med Virol. 1990 Jun;31(2):141-7.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-123523/Enocitabine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-123523/Enocitabine-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
55726-47-1
Available Sizes
Curated Selection
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