Adhesamine
Adhesamine, dumbbell-shaped molecule, activates MAPK/FAK pathway. Adhesamine promotes adhesion and growth of mammalian cells. Adhesamine accelerates the differentiation and improves the survival of mice hippocampal neurons in primary culture[1].
Product Specifications
CAS Number
462605-73-8
UNSPSC
12352005
Target
FAK
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/adhesamine.html
Purity
98.04
Solubility
DMSO : 1 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
O=CC1=C(N=C(SC)N=C1N2CC[N+]3(CC[N+]4(CC3)CCN(CC4)C5=NC(SC)=NC(Cl)=C5C=O)CC2)Cl.[Cl-].[Cl-]
Molecular Formula
C24H32Cl4N8O2S2
Molecular Weight
670.51
References & Citations
[1]Hoshino M, et al. Adhesamine, a new synthetic molecule, accelerates differentiation and prolongs survival of primary cultured mouse hippocampal neurons. Biochem J. 2010 Mar 29;427 (2) :297-304.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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