DBCO-NHCO-PEG3-Fmoc
Product Specifications
UNSPSC Description
DBCO-NHCO-PEG3-Fmoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-NHCO-PEG3-Fmoc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dbco-nhco-peg3-fmoc.html
Smiles
O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)NCCOCCOCCOCCC(NCCC(N4CC(C=CC=C5)=C5C#CC6=C4C=CC=C6)=O)=O
Molecular Weight
701.81
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-133472/DBCO-NHCO-PEG3-Fmoc-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-133472/DBCO-NHCO-PEG3-Fmoc-SDS-MedChemExpress.pdf
Available Sizes
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