6-Mercaptopurine hydrate (Standard)

6-Mercaptopurine hydrate (Standard) is the analytical standard of 6-Mercaptopurine hydrate. This product is intended for research and analytical applications. 6-Mercaptopurine hydrate (Mercaptopurine hydrate; 6-MP hydrate) is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive agent.

Product Specifications

CAS Number

[6112-76-1]

Product Name Alternative

Mercaptopurine hydrate (Standard) ; 6-MP hydrate (Standard)

UNSPSC

12352005

Hazard Statement

H301, H341, H361, H402

Target

Nucleoside Antimetabolite/Analog; Reference Standards

Type

Reference Standards

Related Pathways

Cell Cycle/DNA Damage; Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/6-mercaptopurine-hydrate-standard.html

Purity

99.45

Smiles

S=C1NC=NC2=C1NC=N2.O

Molecular Formula

C5H6N4OS

Molecular Weight

170.19

Precautions

H301, H341, H361, H402

References & Citations

[1]Sahasranaman S, et al. Clinical pharmacology and pharmacogenetics of thiopurines. Eur J Clin Pharmacol. 2008 Aug;64 (8) :753-67.|[2]Liu Q, et al. 6-Mercaptopurine augments glucose transport activity in skeletal muscle cells in part via a mechanism dependent upon orphan nuclear receptor NR4A3. Am J Physiol Endocrinol Metab. 2013 Nov 1;305 (9) :E1081-92.|[3]Kanemitsu H, et al. 6-Mercaptopurine (6-MP) induces cell cycle arrest and apoptosis of neural progenitor cells in the developing fetal rat brain. Neurotoxicol Teratol. 2009 Mar-Apr;31 (2) :104-9.