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TRI37 rabbit pAb

This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. [provided by RefSeq, Mar 2016],

Product Specifications

Background

This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. [provided by RefSeq, Mar 2016]

Product Name Alternative

E3 ubiquitin-protein ligase TRIM37 (EC 6.3.2.-) (Mulibrey nanism protein) (Tripartite motif-containing protein 37)

UniProt

O94972

Swiss Prot

O94972

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from human TRI37 AA range: 315-365

Target

TRI37

Clonality

Polyclonal

Source

Rabbit

Applications

WB

Concentration

1 mg/ml

Dilution

WB 1:500-2000

Buffer

-20°C/1 year

Molecular Weight

105kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

105kD

Fragment

IgG

Subcellular Location

Cytoplasm, perinuclear region . Peroxisome . Found in vesicles of the peroxisome. Aggregates as aggresomes, a perinuclear region where certain misfolded or aggregated proteins are sequestered for proteasomal degradation. .

Other Product Names

E3 ubiquitin-protein ligase TRIM37 (EC 6.3.2.-) (Mulibrey nanism protein) (Tripartite motif-containing protein 37)

Gene ID (Human)

4591

Available Sizes

Curated Selection

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