Ataquimast
Ataquimast is a COX-2 inhibitor that inhibits the release of leukotrienes, TNF-α and GM-CSF. Ataquimast can be used in the study of advanced receptor-positive breast cancer[1].
Product Specifications
CAS Number
182316-31-0
UNSPSC
12352005
Target
C-Fms; COX; Leukotriene Receptor; TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis; GPCR/G Protein; Immunology/Inflammation; Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ataquimast.html
Solubility
10 mM in DMSO
Smiles
O=C1N(CC)C2=C(C=CC=C2)N=C1NC.[H]Cl
Molecular Formula
C11H14ClN3O
Molecular Weight
239.70
References & Citations
[1]Kobayashi Y, et al., Highly efficient synthesis of quinoxalinone-N-oxide via tandem nitrosation/aerobic oxidative C-N bond formation. Org Lett. 2011 Dec 2;13 (23) :6280-3.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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