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Ataquimast

Ataquimast is a COX-2 inhibitor that inhibits the release of leukotrienes, TNF-α and GM-CSF. Ataquimast can be used in the study of advanced receptor-positive breast cancer[1].

Product Specifications

CAS Number

182316-31-0

UNSPSC

12352005

Target

C-Fms; COX; Leukotriene Receptor; TNF Receptor

Type

Reference compound

Related Pathways

Apoptosis; GPCR/G Protein; Immunology/Inflammation; Protein Tyrosine Kinase/RTK

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ataquimast.html

Solubility

10 mM in DMSO

Smiles

O=C1N(CC)C2=C(C=CC=C2)N=C1NC.[H]Cl

Molecular Formula

C11H14ClN3O

Molecular Weight

239.70

References & Citations

[1]Kobayashi Y, et al., Highly efficient synthesis of quinoxalinone-N-oxide via tandem nitrosation/aerobic oxidative C-N bond formation. Org Lett. 2011 Dec 2;13 (23) :6280-3.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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