Molidustat
Molidustat (BAY 85-3934) is an orally active inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH) with IC50 values of 480 nM, 280 nM, and 450 nM for PHD1, PHD2, and PHD3, respectively. Molidustat can elevate the levels of circulating erythropoietin (EPO) to near-normal physiological ranges. Molidustat can be utilized in the research of renal anemia[1][2].
Product Specifications
CAS Number
1154028-82-6
Product Name Alternative
BAY 85-3934
UNSPSC
12352005
Hazard Statement
H302, H360, H372
Target
HIF/HIF Prolyl-Hydroxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Molidustat.html
Purity
99.70
Solubility
DMSO : 5 mg/mL (ultrasonic)
Smiles
O=C1C(N2N=NC=C2)=CNN1C3=NC=NC(N4CCOCC4)=C3
Molecular Formula
C13H14N8O2
Molecular Weight
314.30
Precautions
H302, H360, H372
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
Frequently Asked Questions
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