Miridesap

Miridesap is a ligand for serum amyloid P component (SAP) and intends to inhibit and dissociate SAP binding to amyloid fibrils and tangles.

Product Specifications

CAS Number

[224624-80-0]

Product Name Alternative

CPHPC; Ro63-8695; GSK2315698

UNSPSC

12352005

Hazard Statement

H314

Target

Amyloid-β

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Miridesap.html

Purity

99.19

Solubility

DMSO : 75 mg/mL (ultrasonic) |H2O : 10 mg/mL (ultrasonic)

Smiles

O=C(N1[C@H](CCC1)C(O)=O)CCCCC(N2[C@H](CCC2)C(O)=O)=O

Molecular Formula

C16H24N2O6

Molecular Weight

340.37

Precautions

H314

References & Citations

[1]Kolstoe SE, et al. Molecular dissection of Alzheimer's disease neuropathology by depletion of serum amyloid P component. Proc Natl Acad Sci U S A. 2009 May 5;106 (18) :7619-23.|[2]Sahota T, et al. Target Mediated Drug Disposition Model of CPHPC in Patients with Systemic Amyloidosis. CPT Pharmacometrics Syst Pharmacol. 2015 Feb;4 (2) :e15.