Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

EGFR, Human (sf9, His-GST)

EGFR is a transmembrane glycoprotein. EGFR binds to ligands, triggering receptor dimerization, inducing intracellular TK domain autophosphorylation, activating downstream Ras/MAPK, PI3K/Akt and other signaling pathways, and regulating cell proliferation, survival, migration and angiogenesis. EGFR Protein, Human (sf9, His-GST) is a recombinant EGFR protein expressed by Sf9 insect cells with N-His, N-GST tags.

Product Specifications

Product Name Alternative

EGFR Protein, Human (sf9, His-GST), Human, Sf9 insect cells

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/egfr-protein-human-sf9-his-gst.html

Purity

90.00

Smiles

MRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA

Molecular Formula

1956 (Gene_ID) P00533-1 (M668-A1210) (Accession)

Molecular Weight

Approximately 89.1 kDa

References & Citations

[1]Lemmon M A, et al. Cell signaling by receptor tyrosine kinases. Cell, 2010, 141 (7) : 1117-1134.|[2]Giaccone G. HER1/EGFR-targeted agents: predicting the future for patients with unpredictable outcomes to therapy. Ann Oncol. 2005 Apr;16 (4) :538-48.|[3]Yarden Y, et al. Untangling the ErbB signalling network. Nat Rev Mol Cell Biol. 2001 Feb;2 (2) :127-37. |[4]Shepard HM, et al. Signal integration: a framework for understanding the efficacy of therapeutics targeting the human EGFR family. J Clin Invest. 2008 Nov;118 (11) :3574-81.|[5]Okines A, et al. Targeting the human EGFR family in esophagogastric cancer. Nat Rev Clin Oncol. 2011 Apr 5;8 (8) :492-503.|[6]Ho ECH, et al. Characterization of monoclonal antibodies generated to the 287-302 amino acid loop of the human epidermal growth factor receptor'. Antib Ther. 2019 Oct;2 (4) :88-98.

Shipping Conditions

Dry ice

Storage Conditions

Stored at -80°C for 1 year

Scientific Category

Recombinant Proteins

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Ube2g2 Mouse shRNA Plasmid (Locus ID 22213)
TR502367 1 Kit

Ube2g2 Mouse shRNA Plasmid (Locus ID 22213)

Sign In for Pricing
View Details
Recombinant Bacillus anthracis Aspartate carbamoyltransferase (pyrB)
MBS1300165-01 0.02 mg (E-Coli)

Recombinant Bacillus anthracis Aspartate carbamoyltransferase (pyrB)

Sign In for Pricing
View Details
Recombinant Bacillus anthracis Aspartate carbamoyltransferase (pyrB)
MBS1300165-02 0.02 mg (Yeast)

Recombinant Bacillus anthracis Aspartate carbamoyltransferase (pyrB)

Sign In for Pricing
View Details
Recombinant Bacillus anthracis Aspartate carbamoyltransferase (pyrB)
MBS1300165-03 0.1 mg (E-Coli)

Recombinant Bacillus anthracis Aspartate carbamoyltransferase (pyrB)

Sign In for Pricing
View Details
Recombinant Bacillus anthracis Aspartate carbamoyltransferase (pyrB)
MBS1300165-04 0.1 mg (Yeast)

Recombinant Bacillus anthracis Aspartate carbamoyltransferase (pyrB)

Sign In for Pricing
View Details
Recombinant Bacillus anthracis Aspartate carbamoyltransferase (pyrB)
MBS1300165-05 0.02 mg (Baculovirus)

Recombinant Bacillus anthracis Aspartate carbamoyltransferase (pyrB)

Sign In for Pricing
View Details