Ginkgolic Acid (C13:0)

Ginkgolic Acid (C13:0) (Ginkgoneolic Acid) is an anti-cariogenic agent and a PI3Kδ inhibitor (IC50: 2.49 μM) . Ginkgolic Acid (C13:0) exhibits antibacterial and anti-parasitic activities. Ginkgolic Acid (C13:0) can also inhibit mast cell degranulation (IC50: 2.40 μM) [1][2][3].

Product Specifications

CAS Number

[20261-38-5]

Product Name Alternative

Ginkgolic acid (13:0) ; Ginkgoneolic Acid; 6-Tridecylsalicylic acid

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Bacterial; Parasite; PI3K

Type

Natural Products

Related Pathways

Anti-infection; PI3K/Akt/mTOR

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Ginkgolic-Acid-C13:0.html

Purity

99.92

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(O)C1=C(CCCCCCCCCCCCC)C=CC=C1O

Molecular Formula

C20H32O3

Molecular Weight

320.47

Precautions

H302, H315, H319, H335

References & Citations

[1]He J, et al. Effects of ginkgoneolic acid on the growth, acidogenicity, adherence, and biofilm of Streptococcus mutans in vitro. Folia Microbiol (Praha) . 2013 Mar;58 (2) :147-53.|[2]Guo JF, et al. Discovery of a natural PI3Kδ inhibitor through virtual screening and biological assay study. Biochem Biophys Res Commun. 2019 Jan 15;508 (3) :709-714.|[3]Wang G X, et al. In vivo assessment of anthelmintic efficacy of ginkgolic acids (C13: 0, C15: 1) on removal of Pseudodactylogyrus in European eel. Aquaculture, 2009, 297 (1-4) : 38-43.