(3S,4S) -Tivantinib
(3S,4S) -Tivantinib is a potent and highly selective inhibitor of the receptor tyrosine kinase c-MET. (3S,4S) -Tivantinib has two novel targets, GSK3α and GSK3β, which play an important role in the cellular mechanism of non-small cell lung cancer (NSCLC) [1].
Product Specifications
CAS Number
[905854-03-7]
Product Name Alternative
(3S,4S) -ARQ 197; ARQ 198
UNSPSC
12352005
Hazard Statement
H302, H315, H320, H335
Target
C-Met/HGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3s-4s-tivantinib.html
Purity
98.71
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C(N1)[C@@H]([C@H](C1=O)C2=CNC3=C2C=CC=C3)C4=CN5CCCC6=C5C4=CC=C6
Molecular Formula
C23H19N3O2
Molecular Weight
369.42
Precautions
H302, H315, H320, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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