Orexin 2 Receptor Agonist
Orexin 2 Receptor Agonist is a potent selective OX2R agonist with an EC50 of 23 nM[1].
Product Specifications
CAS Number
[1796565-52-0]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Orexin Receptor (OX Receptor)
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Orexin-2-Receptor-Agonist.html
Concentration
10mM
Purity
99.59
Solubility
DMSO : ≥ 32 mg/mL
Smiles
O=C(C1=CC=CC(C)=C1)NCCNC2=CC(NS(C3=C(OC)C=CC(C4=CC(C(N(C)C)=O)=CC=C4)=C3)(=O)=O)=CC=C2
Molecular Formula
C32H34N4O5S
Molecular Weight
586.70
Precautions
H302, H315, H319, H335
References & Citations
[1]Nagahara T, et al. Design and Synthesis of Non-Peptide, Selective Orexin Receptor 2 Agonists. J Med Chem. 2015 Oct 22;58 (20) :7931-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
OX2 Receptor
Available Sizes
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