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Orexin 2 Receptor Agonist

Orexin 2 Receptor Agonist is a potent selective OX2R agonist with an EC50 of 23 nM[1].

Product Specifications

CAS Number

[1796565-52-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Orexin Receptor (OX Receptor)

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/Orexin-2-Receptor-Agonist.html

Concentration

10mM

Purity

99.59

Solubility

DMSO : ≥ 32 mg/mL

Smiles

O=C(C1=CC=CC(C)=C1)NCCNC2=CC(NS(C3=C(OC)C=CC(C4=CC(C(N(C)C)=O)=CC=C4)=C3)(=O)=O)=CC=C2

Molecular Formula

C32H34N4O5S

Molecular Weight

586.70

Precautions

H302, H315, H319, H335

References & Citations

[1]Nagahara T, et al. Design and Synthesis of Non-Peptide, Selective Orexin Receptor 2 Agonists. J Med Chem. 2015 Oct 22;58 (20) :7931-7.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

OX2 Receptor

Available Sizes

Curated Selection

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