IACS-8968 (R-enantiomer)
Selected Variant
HY-112164A-01
Size: 5 mg
IACS-8968 (R-enantiomer) is the R-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor, with pIC50s of 6.43 for IDO and <5 for TDO, respectively.
Product Specifications
CAS Number
2239305-67-8
Product Name Alternative
IDO/TDO Inhibitor (R-enantiomer)
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/IDO/TDO_Inhibitor_R-enantiomer.html
Concentration
10mM
Purity
98.48
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(N1)N[C@]2(C(C)(C)CN(C3=CC(C(F)(F)F)=CC4=CN=CN34)CC2)C1=O
Molecular Formula
C17H18F3N5O2
Molecular Weight
381.35
References & Citations
[1]ARYL SULFONOHYDRAZIDES. WO 2017189386 A1
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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