IACS-8968 (R-enantiomer)
Product Specifications
UNSPSC Description
IACS-8968 (R-enantiomer) is the R-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor, with pIC50s of 6.43 for IDO and <5 for TDO, respectively.
Target Antigen
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/IDO/TDO_Inhibitor_R-enantiomer.html
Purity
98.48
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(N1)N[C@]2(C(C)(C)CN(C3=CC(C(F)(F)F)=CC4=CN=CN34)CC2)C1=O
Molecular Weight
381.35
References & Citations
[1]ARYL SULFONOHYDRAZIDES. WO 2017189386 A1
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-112164A/IACS-8968-R-enantiomer-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-112164A/IACS-8968-R-enantiomer-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
9007-83-4
Available Sizes
Curated Selection
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