Kaliotoxin (1-37)

<strong>Kaliotoxin (1-37)</strong> <strong>Catalog number:</strong> MDP0635 <strong>CAS Number: </strong>51833-78-4 <strong>Sequence: </strong>Gly-Val-Glu-Ile-Asn-Val-Lys-Cys-Ser-Gly-Ser-Pro-Gln-Cys-Leu-Lys-Pro-Cys-Lys-Asp-Ala-Gly-Met-Arg-Phe-Gly-Lys-Cys-Met-Asn-Arg-Lys-Cys-His-Cys-Thr-Pro (Reported disulfide bonds between Cys8-Cys28, Cys14-Cys33, and Cys18-Cys35) <strong>Amount:</strong> 100 ug <strong>Molecular Weight:</strong> 4021.6 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Kourrich S, Mourre C, Soumireu-Mourat B. Kaliotoxin, a Kv1.1 and Kv1.3 channel blocker, improves associative learning in rats Behav Brain Res. 2001 Apr 8;120(1):35-46. 2: Pentelute BL, Mandal K, Gates ZP, Sawaya MR, Yeates TO, Kent SB. Total chemical synthesis and X-ray structure of kaliotoxin by racemic protein crystallography Chem Commun (Camb). 2010 Nov 21;46(43):8174-6. 3: Ladjel-Mendil A, Martin-Eauclaire MF, Laraba-Djebari F. Neuro-Modulation of Immuno-Endocrine Response Induced by Kaliotoxin of Androctonus Scorpion Venom J Biochem Mol Toxicol. 2016 Dec;30(12):580-587. 4: Crest M, Jacquet G, Gola M, Zerrouk H, Benslimane A, Rochat H, Mansuelle P, Martin-Eauclaire MF. Kaliotoxin, a novel peptidyl inhibitor of neuronal BK-type Ca(2+)-activated K+ channels characterized from Androctonus mauretanicus mauretanicus venom J Biol Chem. 1992 Jan 25;267(3):1640-7. 5: Laraba-Djebari F, Legros C, Crest M, Céard B, Romi R, Mansuelle P, Jacquet G, van Rietschoten J, Gola M, Rochat H, et al. The kaliotoxin family enlarged. Purification, characterization, and precursor nucleotide sequence of KTX2 from Androctonus australis venom J Biol Chem. 1994 Dec 30;269(52):32835-43. 6: Bessone R, Martin-Eauclaire MF, Crest M, Mourre C. Heterogeneous competition of Kv1 channel toxins with kaliotoxin for binding in rat brain: autoradiographic analysis Neurochem Int. 2004 Dec;45(7):1039-47. 7: Abbas N, Belghazi M, Abdel-Mottaleb Y, Tytgat J, Bougis PE, Martin-Eauclaire MF. A new Kaliotoxin selective towards Kv1.3 and Kv1.2 but not Kv1.1 channels expressed in oocytes Biochem Biophys Res Commun. 2008 Nov 21;376(3):525-30. 8: Ladjel-Mendil A, Martin-Eauclaire MF, Laraba-Djebari F. Neuropathophysiological effect and immuno-inflammatory response induced by kaliotoxin of androctonus scorpion venom Neuroimmunomodulation. 2013;20(2):99-106. 9: Romi R, Crest M, Gola M, Sampieri F, Jacquet G, Zerrouk H, Mansuelle P, Sorokine O, Van Dorsselaer A, Rochat H, et al. Synthesis and characterization of kaliotoxin. Is the 26-32 sequence essential for potassium channel recognition? J Biol Chem. 1993 Dec 15;268(35):26302-9. <a href="https://pubmed.ncbi.nlm.nih.gov/10077265">10: Canto J, Fernandez Y, Pons M, Giralt E, Perez JJ. Molecular dynamics study of kaliotoxin in water Int J Biol Macromol. 1999 Jan;24(1):1-9. </a> <br><strong>Products Related to Kaliotoxin (1-37) can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>