A110
A110 is the inhibitor for Cryptosporidium parvum inosine monophosphate dehydrogenase (CpIMPDH) . A110 inhibits CpIMPDH in Toxoplasma gondii with IC50 of 18 nM. A110 exhibits pro-parasitic efficacy and cause parasitemia[1].
Product Specifications
CAS Number
1185388-35-5
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/a110.html
Smiles
C[C@@H](OC1=C2C=CC=CC2=[N+](C=C1)[O-])C3=CN(N=N3)C4=CC=C(C=C4)Cl
Molecular Formula
C19H15ClN4O2
Molecular Weight
366.80
References & Citations
[1]Gorla SK, et al., Validation of IMP dehydrogenase inhibitors in a mouse model of cryptosporidiosis. Antimicrob Agents Chemother. 2014;58 (3) :1603-14.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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