JNK-IN-18
JNK-IN-18 (compund 23b) is a JNK1 inhibitor with IC50 of 2 nM, compared to JNK2 and BRAF (V600E) with IC50 of 125 nM and 98 nM, respectively[1].
Product Specifications
UNSPSC
12352005
Target
JNK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/jnk-in-18.html
Smiles
O=S(C1=CC=C(F)C=C1)(NCCCNC2=NC=CC(C3=CN(CC)N=C3C4=CC=CC(O)=C4)=C2)=O
Molecular Formula
C25H26FN5O3S
Molecular Weight
495.57
References & Citations
[1]Abdel-Maksoud MS, et al. Anticancer and anti-inflammatory effects of novel ethyl pyrazole derivatives having sulfonamide terminal moiety. Bioorg Chem. 2024 Dec;153:107825.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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