Purified Anti-Mouse CD1d Antibody[1B1]
Product Specifications
Background
CD1d, known as CD1.1 and Ly-38, is a 48 kD type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. In humans, CD1 family consists of group I proteins (CD1a, CD1b, and CD1c), group II (CD1d), and group III (CD1e) . But CD1d is the only CD1 molecule has been found in mouse. Mouse CD1d has broad tissue distribution, and is found on leukocytes, dendritic cells, epithelial cells, and thymocytes. CD1d plays a role in non-peptide glycolipid antigen presentation to CD1d-restricted T cells. It has been shown that PKCδ is a critical regulator of CD1d-mediated antigen presentation.
Abbreviation
CD1d
Gene ID
12479
UniProt
P11609
Host
Rat
Reactivity
Mouse
Immunogen
Recombinant Mouse CD1d protein
Target
Antigen-presenting glycoprotein CD1d; Antigen-presenting glycoprotein CD1d1; CD1d.1; Cd1.1; Cd1d1; CD1; Ly-38; CD1.1; CD1.2; AI747460; Cd1a; Cd1d; Ly-38
Clonality
Monoclonal
Clone
1B1
Conjugation
Unconjugated
Applications
FCM
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Isotype
Rat IgG2b, κ
Available Sizes
Curated Selection
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