Anti-Bov CD45R Alexa Fluor® 488

*Naessens J, Howard CJ, Hopkins J: Nomenclature and characterization of leukocyte differentiation antigens in ruminants. Immunol Today. 1997 Aug;18 (8) :365-8., URL: https://www.ncbi.nlm.nih.gov/pubmed/9267076?dopt=A, *Naessens J & Hopkins J: Proceedings of the 3rd workshop on ruminant leukocyte antigens. Davis, California, 16 July 1995. Vet Immunol Immunopathol 52:213-468 (1996) ., URL: https://www.ncbi.nlm.nih.gov/pubmed/8896204?dopt=A, *Sopp P, Howard CJ: Investigation of PC36 (BoCD45R) . Vet Immunol Immunopathol. 1996 Aug;52 (4) :271-4., URL: https://www.ncbi.nlm.nih.gov/pubmed/8896215?dopt=A

The antibody IVA103 reacts with an extracellular epitope of CD45R antigen (bovine), a single chain type I transmembrane glycoprotein (member of the protein tyrosine phosphatase family), a restricted form of the CD45 family. CD45R is an essential regulator of T and B lymphocytes antigen receptor signaling and it is specifically expressed in hematopoietic cells.