Anti-Hu CD41/CD61 (PAC-1 epitope) Alexa Fluor® 488
CD41 (platelet glycoprotein IIb, integrin alpha IIb) is composed of two subunits (120 kDa transmembrane alpha chain and 23 kDa extracellular beta chain) and interacts with CD61 (platelet glycoprotein IIIa, integrin beta 3) in the presence of calcium to form a functional adhesive protein receptor. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin, and it is involved in platelet aggregation.
Product Specifications
Certification
RUO
Reactivity
Human
Immunogen
Human platelets
Target Antigen
CD41/CD61 (PAC-1 epitope)
Clone
PAC-1
Applications
ICC, FC (QC tested)
Format
Alexa Fluor® 488
Buffer
Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
References & Citations
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Specificity
Applications Notes
6
Isotype
Mouse IgM kappa
Frequently Asked Questions
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