What is the catalog number for Anti-Hu CLEC2 PE?

The catalog number for Anti-Hu CLEC2 PE is 1P-892-T100.

What sizes are available for Anti-Hu CLEC2 PE?

Anti-Hu CLEC2 PE is available in the following size(s): 100 Tests.

Is Anti-Hu CLEC2 PE in stock?

Anti-Hu CLEC2 PE is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Anti-Hu CLEC2 PE?

Anti-Hu CLEC2 PE is manufactured by AFG-XBO.

What is the estimated delivery time for Anti-Hu CLEC2 PE?

Estimated delivery time for Anti-Hu CLEC2 PE is approximately 10 business day(s), depending on your location.

Anti-Hu CLEC2 PE

CLEC2 (C-type lectin-like receptor 2) functions as a platelet receptor for the lymphatic endothelial marker, PDPN, and mediates platelet activation. Besides platelets, it can be found on myeloid cells and NK cells. CLEC2 functions also as an attachment factor for HIV-1 and facilitates its capture by platelets. Platelet-aggregating snake venom protein rhodocytin also binds to CLEC2.

Product Specifications

Certification

RUO

Reactivity

Human

Immunogen

A recombinant extracellular domain of human CLEC2 (amino acids 68-229)

Target Antigen

CLEC2

Clone

AYP1

Applications

FC (QC tested)

Format

PE

Buffer

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

References & Citations

*Gitz E, Pollitt AY, Gitz-Francois JJ, Alshehri O, Mori J, Montague S, Nash GB, Douglas MR, Gardiner EE, Andrews RK, Buckley CD, Harrison P, Watson SP: CLEC-2 expression is maintained on activated platelets and on platelet microparticles. Blood 2014 Oct 2;124 (14) :2262-70, URL: https://pubmed.ncbi.nlm.nih.gov/25150298/, *Sung PS, Huang TF, Hsieh SL: Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2. Nat Commun. 2019 Jun 3;10 (1) :2402 , URL: https://pubmed.ncbi.nlm.nih.gov/31160588/

Storage Conditions

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Specificity

The mouse monoclonal antibody AYP1 recognizes an epitope within the extracellular part of CLEC2, a transmembrane glycoprotein expressed on activated plateles and on platelet microparticles.