Anti-Hu CD51/CD61 PE
CD51/CD61 (integrin alpha5beta3), also known as osteoclast functional antigen, serves as a vitronectin receptor, and binds also to fibronectin, fibrinogen, thrombospondin, osteopontin, collagen, and von Willebrand factor. Expression of this antigen increases with melanoma progression. In healthy individuals CD51/CD61 is expressed mainly on osteoclasts, placenta, and endothelial cells, at lower levels on platelets and macrophages.
Product Specifications
Certification
RUO
Negative Species
Rabbit,Pig,Cow
Reactivity
Human, Chicken
Immunogen
A cell suspension containing osteoclasts from osteoclastomas
Target Antigen
CD51/CD61
Clone
23C6
Applications
FC (QC tested)
Format
PE
Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Specificity
Applications Notes
6
Isotype
Mouse IgG1
Frequently Asked Questions
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