Anti-Hu CD172a PE

*Baba T, Badr Mel S, Tomaru U, Ishizu A, Mukaida N: Novel process of intrathymic tumor-immune tolerance through CCR2-mediated recruitment of Sirpα+ dendritic cells: a murine model. PLoS One. 2012;7 (7) :e41154. doi: 10.1371/journal.pone.0041154., URL: https://www.ncbi.nlm.nih.gov/pubmed/22815949, *Hansen IS, Krabbendam L, Bernink JH, Loayza-Puch F, Hoepel W, van Burgsteden JA, Kuijper EC, Buskens CJ, Bemelman WA, Zaat SAJ, Agami R, Vidarsson G, van den Brink GR, de Jong EC, Wildenberg ME, Baeten DLP, Everts B, den Dunnen J: FcαRI co-stimulation converts human intestinal CD103+ dendritic cells into pro-inflammatory cells through glycolytic reprogramming. Nat Commun. 2018 Feb 28;9 (1) :863., URL: https://pubmed.ncbi.nlm.nih.gov/29491406/

*Liu Y, Bühring HJ, Zen K, Burst SL, Schnell FJ, Williams IR, Parkos CA: Signal regulatory protein (SIRPalpha), a cellular ligand for CD47, regulates neutrophil transmigration. J Biol Chem. 2002 Mar 22;277 (12) :10028-36., URL: https://pubmed.ncbi.nlm.nih.gov/11792697/, *Seiffert M, Brossart P, Cant C, Cella M, Colonna M, Brugger W, Kanz L, Ullrich A, Bühring HJ: Signal-regulatory protein alpha (SIRPalpha) but not SIRPbeta is involved in T-cell activation, binds to CD47 with high affinity, and is expressed on immature CD34 (+) CD38 (-) hematopoietic cells. Blood. 2001 May 1;97 (9) :2741-9., URL: https://pubmed.ncbi.nlm.nih.gov/11313266/

The mouse monoclonal antibody 15-414 recognizes en extracellular epitope of CD172a (SIRP alpha), an approximately 90 kDa transmembrane glycoprotein expressed on cells of myeloid origin and neurons.