Anti-Ms CD49e PE
CD49e, the alpha 5 integrin, noncovalently associates with the beta 1integrin (CD29) to form VLA-5 integrin complex. CD49e itself is composed of two disulfide-linked chains of 135 kDa and 25 kDa. VLA-5 binds to RGD sequence of fibronectin, and to neural adhesion molecule L1. It is important in maintaining the integrity of endothelial monolayers, in monocyte migration into the extracellular tissues, and it also provides a co-stimulatory signal to T cells and enhances receptor and complement receptor-mediated phagocytosis.
Product Specifications
Certification
RUO
Immunogen
C57BL/6 x A/J) F1 murine mast cell line
Target Antigen
CD49e
Clone
5H10-27 (MFR5)
Applications
FC (QC tested)
Concentration
0.5 mg/mL
Format
PE
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Specificity
Applications Notes
Flow cytometry: Recommended dilution: 1-4 μg/ml.
Species
Mouse
CAS Number
9007-83-4
Isotype
Rat IgG2a kappa
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