Anti-Hu CD340 FITC
The oncoprotein ErbB2/HER2 (human epidermal growth factor receptor 2), also known as Neu or CD340, is a 185 kDa transmembrane tyrosine kinase of cell surface growth factor receptor family. It is present in a wide variety cell types of normal human fetal and adult tissues and is frequently overexpressed in human carcinomas (e.g. in 20-30% cases of breast cancer cells) . Activation of ErbB2 triggers intracellular signalling events, which are essential for cell growth and differentiation. In the last 25 years ErbB2 antigen has become very important marker and therapy target in patient care.
Product Specifications
Certification
RUO
Immunogen
NIH-3T3/huCD340 cells
Target Antigen
CD340
Clone
24D2
Applications
FC (QC tested)
Format
FITC
Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
Other References
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Specificity
Applications Notes
6
Species
Human
CAS Number
9007-83-4
Isotype
Mouse IgG1
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