OUL35

OUL35 (NSC39047) is a potent and selective inhibitor of ARTD10 (PARP-10), with an IC50 of 329 nM[1].

Product Specifications

CAS Number

[6336-34-1]

Product Name Alternative

NSC39047

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

PARP

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/oul35.html

Purity

99.80

Solubility

DMSO : 83.33 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(C=C1)OC2=CC=C(C=C2)C(N)=O)N

Molecular Formula

C14H12N2O3

Molecular Weight

256.26

Precautions

H302, H315, H319

References & Citations

[1]Harikanth Venkannagari, et al. Small-Molecule Chemical Probe Rescues Cells from Mono-ADP-Ribosyltransferase ARTD10/PARP10-Induced Apoptosis and Sensitizes Cancer Cells to DNA Damage. Cell Chem Biol. 2016 Oct 20;23 (10) :1251-1260.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PARP10

Available Sizes

Curated Selection

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