Anti-Hu TCR Vgamma9 Purified
TCR Vgamma9 is a variant of TCR gamma chain, that is present on a subset of human gamma/delta T cells. TCR Vgamma9/Vdelta2 T cells are able to recognize and kill various tumor cells, as this receptor heterodimer binds to certain phosphoantigens, expressed by tumors.
Product Specifications
Certification
RUO
Reactivity
Human, Non-human primates
Immunogen
Human T cells
Target Antigen
TCR Vgamma9
Clone
B3
Applications
FC (QC tested)
Concentration
1 mg/mL
Format
Purified
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
*van Rhijn I, van den Berg LH, Ang CW, Admiraal J, Logtenberg T: Expansion of human gammadelta T cells after in vitro stimulation with Campylobacter jejuni. Int Immunol. 2003 Mar;15 (3) :373-82., URL: https://pubmed.ncbi.nlm.nih.gov/12618481/
Storage Conditions
Store at 2-8°C. Do not freeze.
Specificity
The mouse monoclonal antibody B3 recognizes an extracellular epitope of human TCR Vgamma9, a variant of TCR gamma chain, which is expressed on a gamma/delta T cell subpopulation with cytolytic activity against various tumor cells.
Applications Notes
Flow cytometry: Recommended dilution: 1-4 μg/ml
Isotype
Mouse IgG1
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