Anti-Hu CD218a Purified
CD218a, an approximately 62 kDa type I transmembrane glycoprotein, is the alpha subunit of IL-18 receptor heterodimer. It is expressed in various immune cells, including lymphocytes, NK cells, and myeloid cells, as well as in heart, lung, liver, gut and another tissues. IL-18 is a proinflammatory cytokine, that promotes both Th1 and Th2 immune responses, induces IFN-gamma production and activates NK cells.
Product Specifications
Certification
RUO
Reactivity
Human
Immunogen
Human CD218a expressed on a transfected NK0 cell line
Target Antigen
CD218a
Clone
H44
Applications
WB, IHC-P, FC (QC tested), IP, IHC-F
Concentration
1 mg/mL
Format
Purified
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
Storage Conditions
Store at 2-8°C. Do not freeze.
Specificity
The mouse monoclonal antibody H44 recognizes an extracellular epitope of CD218a, the alpha subunit of IL-18 receptor.
Applications Notes
Flow cytometry: Recommended dilution: 1-4 μg/ml.
Isotype
Mouse IgG1 kappa
Frequently Asked Questions
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