Anti-Hu CD307b Purified
CD307b is a type I transmembrane glycoprotein of the Fc receptor family. It contains one ITAM motif and two ITIM motifs in its cytoplasmic domain. It is expressed in spleen and lymph nodes in mature B cells and memory B cells. CD307b may be a prognostic marker for chronic lymphocytic leukemia.
Product Specifications
Certification
RUO
Reactivity
Human
Immunogen
DNA-immunization followed by a boost with CD307b transfected cells
Target Antigen
CD307b
Clone
B24
Applications
FC (QC tested)
Concentration
1 mg/mL
Format
Purified
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
*Nagata S, Ise T, Pastan I: Fc receptor-like 3 protein expressed on IL-2 nonresponsive subset of human regulatory T cells. J Immunol. 2009 Jun 15;182 (12) :7518-26, URL: https://www.ncbi.nlm.nih.gov/pubmed/19494275
Storage Conditions
Store at 2-8°C. Do not freeze.
Specificity
The mouse monoclonal antibody B24 recognizes an extracellular epitope of CD307b, a transmembrane glycoprotein expressed mainly in mature and memory B cells.
Applications Notes
Flow cytometry: Recommended dilution: 1-4 μg/ml.
Isotype
Mouse IgG2a kappa
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