Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-Hu SUSD2

SUSD2 (sushi domain containing protein 2) is a type I transmembrane protein, that serves as an important marker of bone marrow-derived mesenchymal stem-like cells (bone marrow stromal cells) . These pluripotent cells are important for techniques of autologous cell therapy, and can be collected from e.g. endometrium, or palatine tonsil. SUSD2 seems to be a tumor supresor, and is down-regulated in colon cancer tissues, whereas it is highly expressed e.g. in breast cancer.

Product Specifications

Certification

RUO

Immunogen

WERI-RB-1 retinoblastoma cells

Target Antigen

SUSD2

Clone

W5C5

Applications

ICC, FC (QC tested)

Concentration

1 mg/mL

Format

Purified

Buffer

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

References & Citations

*Bredenkamp N, Stirparo GG, Nichols J, Smith A, Guo G: The cell-surface marker sushi containing domain 2 facilitates establishment of human naive pluripotent stem cells. Stem Cell Reports. 2019 Jun 11;12 (6) :1212-1222., URL: https://pubmed.ncbi.nlm.nih.gov/31031191/, *Murakami K, Lee YH, Lucas ES, Chan YW, Durairaj RP, Takeda S, Moore JD, Tan BK, Quenby S, Chan JK, Gargett CE, Brosens JJ: Decidualization induces a secretome switch in perivascular niche cells of the human endometrium. Endocrinology. 2014 Nov;155 (11) :4542-53., URL: https://www.ncbi.nlm.nih.gov/pubmed/25116707, *Lee BJ, Kang DW, Park HY, Song JS, Kim JM, Jang JY, Lee JC, Wang SG, Jung JS, Shin SC: Isolation and Localization of Mesenchymal Stem Cells in Human Palatine Tonsil by W5C5 (SUSD2) . Cell Physiol Biochem. 2016;38 (1) :83-93., URL: https://www.ncbi.nlm.nih.gov/pubmed/26741828, *Bühring HJ, Battula VL, Treml S, Schewe B, Kanz L, Vogel W: Novel markers for the prospective isolation of human MSC. Ann N Y Acad Sci. 2007 Jun;1106:262-71. , URL: https://www.ncbi.nlm.nih.gov/pubmed/17395729, *Sivasubramaniyan K, Harichandan A, Schumann S, Sobiesiak M, Lengerke C, Maurer A, Kalbacher H, Bühring HJ: Prospective isolation of mesenchymal stem cells from human bone marrow using novel antibodies directed against Sushi domain containing 2. Stem Cells Dev. 2013 Jul 1;22 (13) :1944-54., URL: https://www.ncbi.nlm.nih.gov/pubmed/23406305, *Ulrich D, Tan KS, Deane J, Schwab K, Cheong A, Rosamilia A, Gargett CE: Mesenchymal stem/stromal cells in post-menopausal endometrium. Hum Reprod. 2014 Sep;29 (9) :1895-905., URL: https://www.ncbi.nlm.nih.gov/pubmed/24964924

Storage Conditions

Store at 2-8°C. Do not freeze.

Specificity

The mouse monoclonal antibody W5C5 recognizes an extracellular epitope of SUSD2, a type I transmembrane protein expressed on mesenchymal stem-like cells. This antibody selectively binds to a MSCs in both bone marrow and endometrium or tonsil, and can be used for their identification and isolation.

Applications Notes

Flow cytometry: Recommended dilution: 1-4 µg/ml

Species

Human

CAS Number

9007-83-4

Isotype

Mouse IgG1

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

GENLISA™ Monkey for Carcinoembryonic Antigen (CEA) ELISA
KLW0154 96 Well

GENLISA™ Monkey for Carcinoembryonic Antigen (CEA) ELISA

Ask
View Details
Dapk1 (BC060161) Mouse Tagged ORF Clone Lentiviral Particle
MR211125L3V 200 µL

Dapk1 (BC060161) Mouse Tagged ORF Clone Lentiviral Particle

Ask
View Details
PE/Cyanine7 Anti-Mouse CD279/PD-1 Antibody
MBS4516183-01 0.025 mg

PE/Cyanine7 Anti-Mouse CD279/PD-1 Antibody

Ask
View Details
PE/Cyanine7 Anti-Mouse CD279/PD-1 Antibody
MBS4516183-02 0.05 mg

PE/Cyanine7 Anti-Mouse CD279/PD-1 Antibody

Ask
View Details
PE/Cyanine7 Anti-Mouse CD279/PD-1 Antibody
MBS4516183-03 0.1 mg

PE/Cyanine7 Anti-Mouse CD279/PD-1 Antibody

Ask
View Details
PE/Cyanine7 Anti-Mouse CD279/PD-1 Antibody
MBS4516183-04 0.2 mg

PE/Cyanine7 Anti-Mouse CD279/PD-1 Antibody

Ask
View Details