ID2 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein

Gene Aliases

GIG8, ID2A, ID2H, bHLHb26

Gene ID

3398

Accession Number

NP_002157

Reactivity

Human, Mouse, Rat, Cow, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ID2

Target

ID2 belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation.The protein encoded by this gene belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene has been identified for this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

ASB4; UBC; SUV39H2; PRMT6; KDM1A; SUV39H1; TCF12; TCF3; TSTA3; MAPK8; ID2; HSPA5; RBL2; RBL1; RB1; CDK2; USP1; MAPK3; MAPK1; E2F4; SIN3A; GATA4; NKX2-5; LRIF1; PPP1CA; RBM48; NEDD9; UNC119; MSC; TCF4; ELK3; ELK4; ELK1; PAX8; PAX5; PAX2; MYF6; MYF5; MYOG

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

TIVSLHHQRPGQNQASRTPLTTLNTDISILSLQASEFPSELMSNDSKALC

Applications

WB, IHC

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol