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NFKBIL2 Antibody - middle region

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Product Specifications

CAS Number

9007-83-4

Gene Name

Tonsoku-like, DNA repair protein

Gene Aliases

IKBR, SEMDSP, NFKBIL2

Gene ID

4796

Accession Number

NP_038460

Reactivity

Human, Mouse, Rat, Dog

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human NFKBIL2

Target

NFKBIL2 is thought to be a negative regulator of NF-kappa-B mediated transcription. It may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.

Partner Proteins

HIST3H3; MCM6; MCM2; MMS22L; ASF1B; ASF1A; UBC; MYC; MAU2; SLC25A5; SUPT16H; SUGT1; AIFM1; HIST1H2BL; XRCC5; SSRP1; SLC25A3; TONSL; MCM4; HIST1H2AE; HIST1H1B; HIST1H1C; XRCC6; GSK3B; MCM7; MCM5; MCM3; EWSR1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

RAIIHVSLATTLGDMKDHHGAVRHYEEELRLRSGNVLEEAKTWLNIALSR

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Dog: 84%; Human: 100%; Mouse: 83%; Rat: 83%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

133kDa

Protein Length

1219

NCBI Gene Symbol

TONSL

Host or Source

Rabbit

Protein Name

Tonsoku-like protein

Gene Name URL

TONSL

Nucleotide Accession Number

NM_013432

Frequently Asked Questions

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