NFKBIL2 Antibody - middle region
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Product Specifications
CAS Number
9007-83-4
Gene Name
Tonsoku-like, DNA repair protein
Gene Aliases
IKBR, SEMDSP, NFKBIL2
Gene ID
4796
Accession Number
NP_038460
Reactivity
Human, Mouse, Rat, Dog
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human NFKBIL2
Target
NFKBIL2 is thought to be a negative regulator of NF-kappa-B mediated transcription. It may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.
Partner Proteins
HIST3H3; MCM6; MCM2; MMS22L; ASF1B; ASF1A; UBC; MYC; MAU2; SLC25A5; SUPT16H; SUGT1; AIFM1; HIST1H2BL; XRCC5; SSRP1; SLC25A3; TONSL; MCM4; HIST1H2AE; HIST1H1B; HIST1H1C; XRCC6; GSK3B; MCM7; MCM5; MCM3; EWSR1
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
RAIIHVSLATTLGDMKDHHGAVRHYEEELRLRSGNVLEEAKTWLNIALSR
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Dog: 84%; Human: 100%; Mouse: 83%; Rat: 83%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
133kDa
Protein Length
1219
NCBI Gene Symbol
TONSL
Host or Source
Rabbit
Protein Name
Tonsoku-like protein
Gene Name URL
TONSL
Nucleotide Accession Number
NM_013432
Curated Selection
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