RARA Antibody - middle region
Product Specifications
CAS Number
9007-83-4
Gene Name
Retinoic acid receptor, alpha
Gene Aliases
RAR, NR1B1
Gene ID
5914
Accession Number
NP_000955
Reactivity
Human, Mouse, Rat, Cow, Dog, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human RARA
Target
Retinoid signaling is transduced by 2 families of nuclear receptors, retinoic acid receptor (RAR) and retinoid X receptor, which form RXR/RAR heterodimers. In the absence of ligand, DNA-bound RXR/RARA represses transcription by recruiting the corepressors NCOR1, SMRT, and histone deacetylase. When ligand binds to the complex, it induces a conformational change allowing the recruitment of coactivators, histone acetyltransferases, and the basic transcription machinery.
Partner Proteins
NCOR2; NCOR1; RXRG; MED1; HDAC1; NRIP1; TEKT4; NSD1; NCOA1; CEBPA; ITGB1BP2; SUMO1; UBC; MBD3; CBX5; MTA2; E2F1; WWOX; Sumo2; RXRB; RXRA; AKT1; MMS19; Dlg4; TMEM54; FN1; USP7; NCOA2; SUZ12; EZH2; PML; PSMC5; FAS; PRAM1; TBL1XR1; PRAME; ARID5A; UBE3A; UBQL
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
EMLENSEGLDTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHS
Applications
WB, IHC
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Human: 100%; Mouse: 85%; Rabbit: 100%; Rat: 85%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
51kDa
Protein Length
462
NCBI Gene Symbol
RARA
Host or Source
Rabbit
Protein Name
Retinoic acid receptor alpha
Gene Name URL
RARA
Nucleotide Accession Number
NM_000964
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