MEF2C Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Myocyte enhancer factor 2C

Gene Aliases

DEL5q14.3, C5DELq14.3

Gene ID

4208

Accession Number

NP_002388

Reactivity

Human, Mouse, Rat, Dog, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human MEF2C

Target

MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. MEF2C controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. MEF2C may also be involved in neurogenesis and in the development of cortical architecture. Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.

Partner Proteins

PLA2G12A; UBC; ASCL1; SUMO1; HDAC7; HDAC5; HDAC4; MYOD1; IFRD1; NCOA2; SIRT1; HDAC9; COPS5; YWHAZ; SPTBN1; MAPK7; EPAS1; MAPK14; VGLL2; VGLL4; TWIST2; GATA4; SOX18; EP300; SMAD2; MEF2D; MEF2C; NOTCH1; TEAD1; SP1; CCNB1; CDK1; CSNK2A1; MYOG

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

PPSALSQLGACTSTHLSQSSNLSLPSTQSLNIKSEPVSPPRDRTTTPSRY

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

51kDa

Protein Length

473

NCBI Gene Symbol

MEF2C

Host or Source

Rabbit

Protein Name

Myocyte-specific enhancer factor 2C

Gene Name URL

MEF2C

Nucleotide Accession Number

NM_002397

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