HCV Core Protein
Product Specifications
Gene Aliases
HCV Core, Biotin, Hepatitis C Virus Core, Biotin Recombinant
Reactivity
Hepatitis C Virus
Target
HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae._x005F HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes (1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6) .
Type
Protein
Applications
ELISA, WB
Purification
HCV Core protein was purified by proprietary chromatographic technique.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
Varies by lot. See vial for concentration.
Format
Liquid// 20mM Tris-HCl (pH 8.0) and 8M Urea
Reconstitution
HCV Core although stable at 4° C for 1 week, should be stored below -18° C. Please prevent freeze thaw cycles.
Molecular Weight
22 kDa
Notes
Formerly GWB-CE9290
Specificity
Immunoreactive with sera of HCV-infected individuals.
Protein Length
Recombinant
NCBI Gene Symbol
HCV CORE-BIOTIN
Gene Name URL
HCV Core-Biotin
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