TRAIL Protein
Product Specifications
Gene Aliases
TL2, APO2L, CD253, TRAIL, Apo-2L, TNLG6A
Gene ID
8743
Accession Number
NP_003801.1
Reactivity
Human
Target
TNF-related apoptosis-inducing ligand (TRAIL) is a ligand molecule which induces apoptosis. It is a type II transmembrane protein with homology to other members of the tumor necrosis factor family. In humans, the gene that encodes for TRAIL is located at chromosome 3q26. TRAIL binds to the death receptors, DR4 and DR5. The process of apoptosis is caspase-8-dependent. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues.
Type
Protein
Source
E. Coli
Purification
The sTRAIL is purified by proprietary chromatographic techniques.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Bioactivity
50
Format
Lyophilized// from a filtered (0.2μm) solution containing 20mM Tris-HCl pH 8.0 and 150mM NaCl
Physical Appearance:// Sterile filtered white powderPhysical Appearance:// Sterile filtered white powder
Molecular Weight
~21 kDa
Notes
Formerly GWB-63F4CF
Protein Length
Recombinant
NCBI Gene Symbol
TRAIL
Protein Name
Tumor necrosis factor ligand superfamily member 10
Gene Name URL
TRAIL
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