IL1RN Recombinant Protein
Product Specifications
Gene Name
Interleukin 1 receptor antagonist
Gene Aliases
DIRA; ICIL-1RA; IL1 inhibitor; IL1F3; IL-1ra; IL1RA; IL-1ra3; IL-1RN; interleukin-1 receptor antagonist protein; intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1ra) ; IRAP; MVCD4; type II interleukin-1 receptor antagonist.
Gene ID
3557
Accession Number
NP_000568.1
Reactivity
Homo sapiens|Human
Target
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure.
Conjugation
Unconjugated
Type
Protein
Source
293-F Cells
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
22/25/27kDa
Protein Length
Recombinant
NCBI Gene Symbol
IL1RN
Host or Source
293F cell
Protein Name
Interleukin-1 receptor antagonist protein
Gene Name URL
IL1RN
CAS Number
9000-83-3
Nucleotide Accession Number
NM_000577.4
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