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IL1RN Recombinant Protein

Product Specifications

CAS Number

9000-83-3

Gene Name

Interleukin 1 receptor antagonist

Gene Aliases

DIRA; ICIL-1RA; IL1 inhibitor; IL1F3; IL-1ra; IL1RA; IL-1ra3; IL-1RN; interleukin-1 receptor antagonist protein; intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1ra) ; IRAP; MVCD4; type II interleukin-1 receptor antagonist.

Gene ID

3557

Accession Number

NP_000568.1

Reactivity

Homo sapiens|Human

Target

Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure.

Conjugation

Unconjugated

Type

Protein

Source

293-F Cells

Applications

Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

200 ug/mL (prior to lyoph)

Format

Freeze-dried Powder. PBS, pH7.4, containing 5% Trehalose.

Reconstitution

2°C to 8°C|-80°C

Molecular Weight

22/25/27kDa

Protein Length

Recombinant

NCBI Gene Symbol

IL1RN

Host or Source

293F cell

Protein Name

Interleukin-1 receptor antagonist protein

Gene Name URL

IL1RN

Nucleotide Accession Number

NM_000577.4

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